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The transcription factor Bhlhe40 is a switch of inflammatory versus antiinflammatory Th1 cell fate determination
Type 1 T helper (Th1) cells play a critical role in host defense against intracellular pathogens and in autoimmune diseases by producing a key inflammatory cytokine interferon (IFN)–γ; some Th1 cells can also be antiinflammatory through producing IL-10. However, the molecular switch for regulating t...
Autores principales: | Yu, Fang, Sharma, Suveena, Jankovic, Dragana, Gurram, Rama Krishna, Su, Pan, Hu, Gangqing, Li, Rao, Rieder, Sadiye, Zhao, Keji, Sun, Bing, Zhu, Jinfang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028509/ https://www.ncbi.nlm.nih.gov/pubmed/29773643 http://dx.doi.org/10.1084/jem.20170155 |
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