Cargando…

A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival

A20 (TNFAIP3) and ABIN-1 (TNIP1) are candidate susceptibility genes for inflammatory bowel disease and other autoimmune or inflammatory diseases, but it is unclear how these proteins interact in vivo to prevent disease. Here we show that intestinal epithelial cell (IEC)-specific deletion of either A...

Descripción completa

Detalles Bibliográficos
Autores principales: Kattah, Michael G., Shao, Ling, Rosli, Yenny Y., Shimizu, Hiromichi, Whang, Michael I., Advincula, Rommel, Achacoso, Philip, Shah, Sanjana, Duong, Bao H., Onizawa, Michio, Tanbun, Priscilia, Malynn, Barbara A., Ma, Averil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028510/
https://www.ncbi.nlm.nih.gov/pubmed/29930103
http://dx.doi.org/10.1084/jem.20180198