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Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts

Neuronal polarity relies on the selective localization of cargo to axons or dendrites. The molecular motor kinesin-1 moves cargo into axons but is also active in dendrites. This raises the question of how kinesin-1 activity is regulated to maintain the compartment-specific localization of cargo. Our...

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Detalles Bibliográficos
Autores principales: Kelliher, Michael T., Yue, Yang, Ng, Ashley, Kamiyama, Daichi, Huang, Bo, Verhey, Kristen J., Wildonger, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028532/
https://www.ncbi.nlm.nih.gov/pubmed/29728423
http://dx.doi.org/10.1083/jcb.201708096