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Autoinhibition of kinesin-1 is essential to the dendrite-specific localization of Golgi outposts
Neuronal polarity relies on the selective localization of cargo to axons or dendrites. The molecular motor kinesin-1 moves cargo into axons but is also active in dendrites. This raises the question of how kinesin-1 activity is regulated to maintain the compartment-specific localization of cargo. Our...
Autores principales: | Kelliher, Michael T., Yue, Yang, Ng, Ashley, Kamiyama, Daichi, Huang, Bo, Verhey, Kristen J., Wildonger, Jill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028532/ https://www.ncbi.nlm.nih.gov/pubmed/29728423 http://dx.doi.org/10.1083/jcb.201708096 |
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