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Glutathione metabolism in cancer progression and treatment resistance

Glutathione (GSH) is the most abundant antioxidant found in living organisms and has multiple functions, most of which maintain cellular redox homeostasis. GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer cells. However, GS...

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Detalles Bibliográficos
Autores principales: Bansal, Ankita, Simon, M. Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028537/
https://www.ncbi.nlm.nih.gov/pubmed/29915025
http://dx.doi.org/10.1083/jcb.201804161