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Glutathione metabolism in cancer progression and treatment resistance
Glutathione (GSH) is the most abundant antioxidant found in living organisms and has multiple functions, most of which maintain cellular redox homeostasis. GSH preserves sufficient levels of cysteine and detoxifies xenobiotics while also conferring therapeutic resistance to cancer cells. However, GS...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028537/ https://www.ncbi.nlm.nih.gov/pubmed/29915025 http://dx.doi.org/10.1083/jcb.201804161 |