Uncoordinated centrosome cycle underlies the instability of non-diploid somatic cells in mammals

In animals, somatic cells are usually diploid and are unstable when haploid for unknown reasons. In this study, by comparing isogenic human cell lines with different ploidies, we found frequent centrosome loss specifically in the haploid state, which profoundly contributed to haploid instability thr...

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Detalles Bibliográficos
Autores principales: Yaguchi, Kan, Yamamoto, Takahiro, Matsui, Ryo, Tsukada, Yuki, Shibanuma, Atsuko, Kamimura, Keiko, Koda, Toshiaki, Uehara, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028549/
https://www.ncbi.nlm.nih.gov/pubmed/29712735
http://dx.doi.org/10.1083/jcb.201701151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028549/
https://www.ncbi.nlm.nih.gov/pubmed/29712735
http://dx.doi.org/10.1083/jcb.201701151

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