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Ontology and Function of Fibroblast-Like and Macrophage-Like Synoviocytes: How Do They Talk to Each Other and Can They Be Targeted for Rheumatoid Arthritis Therapy?

Fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) are the two main cellular components of the synovium. It has been widely reported that FLS and MLS play essential roles in the joint pathology of rheumatoid arthritis (RA). Although various studies have analyzed both human and...

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Detalles Bibliográficos
Autores principales: Tu, Jiajie, Hong, Wenming, Zhang, Pengying, Wang, Xinming, Körner, Heinrich, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028561/
https://www.ncbi.nlm.nih.gov/pubmed/29997624
http://dx.doi.org/10.3389/fimmu.2018.01467