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HECIL: A Hybrid Error Correction Algorithm for Long Reads with Iterative Learning

Second-generation DNA sequencing techniques generate short reads that can result in fragmented genome assemblies. Third-generation sequencing platforms mitigate this limitation by producing longer reads that span across complex and repetitive regions. However, the usefulness of such long reads is li...

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Detalles Bibliográficos
Autores principales: Choudhury, Olivia, Chakrabarty, Ankush, Emrich, Scott J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028576/
https://www.ncbi.nlm.nih.gov/pubmed/29967328
http://dx.doi.org/10.1038/s41598-018-28364-3