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Image-Based Profiling of Synaptic Connectivity in Primary Neuronal Cell Culture

Neurological disorders display a broad spectrum of clinical manifestations. Yet, at the cellular level, virtually all these diseases converge into a common phenotype of dysregulated synaptic connectivity. In dementia, synapse dysfunction precedes neurodegeneration and cognitive impairment by several...

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Detalles Bibliográficos
Autores principales: Verstraelen, Peter, Van Dyck, Michiel, Verschuuren, Marlies, Kashikar, Nachiket D., Nuydens, Rony, Timmermans, Jean-Pierre, De Vos, Winnok H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028601/
https://www.ncbi.nlm.nih.gov/pubmed/29997468
http://dx.doi.org/10.3389/fnins.2018.00389