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Prenatal immune activation alters the adult neural epigenome but can be partly stabilised by a n-3 polyunsaturated fatty acid diet

An unstable epigenome is implicated in the pathophysiology of neurodevelopmental disorders such as schizophrenia and autism. This is important because the epigenome is potentially modifiable. We have previously reported that adult offspring exposed to maternal immune activation (MIA) prenatally have...

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Detalles Bibliográficos
Autores principales: Basil, Paul, Li, Qi, Gui, Hongsheng, Hui, Tomy C. K., Ling, Vicki H. M., Wong, Chloe C. Y., Mill, Jonathan, McAlonan, Grainne M., Sham, Pak-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028639/
https://www.ncbi.nlm.nih.gov/pubmed/29967385
http://dx.doi.org/10.1038/s41398-018-0167-x