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CEACAM1 promotes CD8(+) T cell responses and improves control of a chronic viral infection

Dysfunction of CD8(+) T cells can lead to the development of chronic viral infection. Identifying mechanisms responsible for such T cell dysfunction is therefore of great importance to understand how to prevent persistent viral infection. Here we show using lymphocytic choriomeningitis virus (LCMV) ...

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Detalles Bibliográficos
Autores principales: Khairnar, Vishal, Duhan, Vikas, Patil, Ashwini M., Zhou, Fan, Bhat, Hilal, Thoens, Christine, Sharma, Piyush, Adomati, Tom, Friendrich, Sarah-Kim, Bezgovsek, Judith, Dreesen, Janine D., Wennemuth, Gunther, Westendorf, Astrid M., Zelinskyy, Gennadiy, Dittmer, Ulf, Hardt, Cornelia, Timm, Jörg, Göthert, Joachim R., Lang, Philipp A., Singer, Bernhard B., Lang, Karl S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028648/
https://www.ncbi.nlm.nih.gov/pubmed/29967450
http://dx.doi.org/10.1038/s41467-018-04832-2