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Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer’s disease

Proteinopathies constitute a group of diseases in which certain proteins are abnormally folded leading to aggregation and eventual cell failure. Most neurodegenerative diseases belong to protein misfolding disorders and, among them, Alzheimer’s disease (AD) is the most prevalent. AD is characterized...

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Detalles Bibliográficos
Autores principales: Martín-Peña, Alfonso, Rincón-Limas, Diego E., Fernandez-Fúnez, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028656/
https://www.ncbi.nlm.nih.gov/pubmed/29967544
http://dx.doi.org/10.1038/s41598-018-28341-w