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Cochlear Gene Therapy for Sensorineural Hearing Loss: Current Status and Major Remaining Hurdles for Translational Success

Sensorineural hearing loss (SNHL) affects millions of people. Genetic mutations play a large and direct role in both congenital and late-onset cases of SNHL (e.g., age-dependent hearing loss, ADHL). Although hearing aids can help moderate to severe hearing loss the only effective treatment for deaf...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjuan, Kim, Sun Myoung, Wang, Wenwen, Cai, Cuiyuan, Feng, Yong, Kong, Weijia, Lin, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028713/
https://www.ncbi.nlm.nih.gov/pubmed/29997477
http://dx.doi.org/10.3389/fnmol.2018.00221