Defect of branched-chain amino acid metabolism promotes the development of Alzheimer’s disease by targeting the mTOR signaling

Diabetes is a risk factor for Alzheimer’s disease (AD) in humans. Branched-chain amino acids (BCAAs, namely valine, leucine, and isoleucine) metabolic defect is observed in human diabetes, which is associated with insulin resistance. But whether BCAAs connect diabetes and AD remains unknown. Here, w...

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Detalles Bibliográficos
Autores principales: Li, Huajie, Ye, Dan, Xie, Wei, Hua, Fei, Yang, Yilin, Wu, Jian, Gu, Aifang, Ren, Yi, Mao, Keshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028749/
https://www.ncbi.nlm.nih.gov/pubmed/29802157
http://dx.doi.org/10.1042/BSR20180127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028749/
https://www.ncbi.nlm.nih.gov/pubmed/29802157
http://dx.doi.org/10.1042/BSR20180127

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