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Oxidative stress induces BH(4) deficiency in male, but not female, SHR

We previously published that female spontaneously hypertensive rats (SHR) have significantly greater nitric oxide (NO) bioavailability and NO synthase (NOS) enzymatic activity in the renal inner medulla (IM) compared with age-matched males, although the mechanism responsible remains unknown. Tetrahy...

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Detalles Bibliográficos
Autores principales: Gillis, Ellen E., Brinson, Krystal N., Rafikova, Olga, Chen, Wei, Musall, Jacqueline B., Harrison, David G., Sullivan, Jennifer C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028750/
https://www.ncbi.nlm.nih.gov/pubmed/29899168
http://dx.doi.org/10.1042/BSR20180111