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Edaravone and cyclosporine A as neuroprotective agents for acute ischemic stroke

It is well known that acute ischemic stroke (AIS) and subsequent reperfusion produce lethal levels of reactive oxygen species (ROS) in neuronal cells, which are generated in mitochondria. Mitochondrial ROS production is a self‐amplifying process, termed “ROS‐induced ROS release”. Furthermore, the mi...

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Detalles Bibliográficos
Autores principales: Matsumoto, Shohei, Murozono, Michihiro, Kanazawa, Masahiro, Nara, Takeshi, Ozawa, Takuro, Watanabe, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028804/
https://www.ncbi.nlm.nih.gov/pubmed/29988669
http://dx.doi.org/10.1002/ams2.343