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Potassium is a trigger for conformational change in the fusion spike of an enveloped RNA virus

Many enveloped viruses enter cells through the endocytic network, from which they must subsequently escape through fusion of viral and endosomal membranes. This membrane fusion is mediated by virus-encoded spikes that respond to the dynamic endosomal environment, which triggers conformational change...

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Detalles Bibliográficos
Autores principales: Punch, Emma K., Hover, Samantha, Blest, Henry T. W., Fuller, Jack, Hewson, Roger, Fontana, Juan, Mankouri, Jamel, Barr, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028977/
https://www.ncbi.nlm.nih.gov/pubmed/29678879
http://dx.doi.org/10.1074/jbc.RA118.002494