Azithromycin enhances anticancer activity of TRAIL by inhibiting autophagy and up-regulating the protein levels of DR4/5 in colon cancer cells in vitro and in vivo

BACKGROUND: Azithromycin is a member of macrolide antibiotics, and has been reported to inhibit the proliferation of cancer cells. However, the underlying mechanisms are not been fully elucidated. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively targets tumor cells without...

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Detalles Bibliográficos
Autores principales: Qiao, Xinran, Wang, Xiaofei, Shang, Yue, Li, Yi, Chen, Shu-zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029027/
https://www.ncbi.nlm.nih.gov/pubmed/29970185
http://dx.doi.org/10.1186/s40880-018-0309-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029027/
https://www.ncbi.nlm.nih.gov/pubmed/29970185
http://dx.doi.org/10.1186/s40880-018-0309-9

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