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TMEM106B haplotypes have distinct gene expression patterns in aged brain

BACKGROUND: Single nucleotide polymorphisms (SNPs) inherited as one of two common haplotypes at the transmembrane protein 106B (TMEM106B) locus are associated with the risk of multiple neurodegenerative diseases, including frontotemporal lobar degeneration with pathological inclusions of TDP-43. Amo...

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Detalles Bibliográficos
Autores principales: Ren, Yingxue, van Blitterswijk, Marka, Allen, Mariet, Carrasquillo, Minerva M., Reddy, Joseph S., Wang, Xue, Beach, Thomas G., Dickson, Dennis W., Ertekin-Taner, Nilüfer, Asmann, Yan W., Rademakers, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029036/
https://www.ncbi.nlm.nih.gov/pubmed/29970152
http://dx.doi.org/10.1186/s13024-018-0268-2