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Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation
BACKGROUND: Silica nanoparticles (SiO(2)-NPs) are naturally enriched and broadly utilized in the manufacturing industry. While previous studies have demonstrated toxicity in neuronal cell lines after SiO(2)-NPs exposure, the role of SiO(2)-NPs in neurodegeneration is largely unknown. Here, we evalua...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029039/ https://www.ncbi.nlm.nih.gov/pubmed/29970116 http://dx.doi.org/10.1186/s12989-018-0263-3 |