Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation

BACKGROUND: Silica nanoparticles (SiO(2)-NPs) are naturally enriched and broadly utilized in the manufacturing industry. While previous studies have demonstrated toxicity in neuronal cell lines after SiO(2)-NPs exposure, the role of SiO(2)-NPs in neurodegeneration is largely unknown. Here, we evalua...

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Detalles Bibliográficos
Autores principales: You, Ran, Ho, Yuen-Shan, Hung, Clara Hiu-Ling, Liu, Yan, Huang, Chun-Xia, Chan, Hei-Nga, Ho, See-Lok, Lui, Sheung-Yeung, Li, Hung-Wing, Chang, Raymond Chuen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029039/
https://www.ncbi.nlm.nih.gov/pubmed/29970116
http://dx.doi.org/10.1186/s12989-018-0263-3

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