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3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase

BACKGROUND: Glioblastoma (GBM) is the most common, malignant, and lethal primary brain tumor in adults accounting for about 50% of all gliomas. Up to now, the chemotherapy approaches for GBM were limited. 3-O-acetyl-11-keto-β-boswellic acid (AKBA), the major active ingredient of the gum resin from B...

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Detalles Bibliográficos
Autores principales: Li, Wan, Liu, Jinyi, Fu, Weiqi, Zheng, Xiangjin, Ren, Liwen, Liu, Shiwei, Wang, Jinhua, Ji, Tengfei, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029111/
https://www.ncbi.nlm.nih.gov/pubmed/29970196
http://dx.doi.org/10.1186/s13046-018-0805-4