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Reduced cellularity of bone marrow in multiple sclerosis with decreased MSC expansion potential and premature ageing in vitro

BACKGROUND: Autologous bone-marrow-derived cells are currently employed in clinical studies of cell-based therapy in multiple sclerosis (MS) although the bone marrow microenvironment and marrow-derived cells isolated from patients with MS have not been extensively characterised. OBJECTIVES: To exami...

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Detalles Bibliográficos
Autores principales: Redondo, Juliana, Sarkar, Pamela, Kemp, Kevin, Virgo, Paul F, Pawade, Joya, Norton, Aimie, Emery, David C, Guttridge, Martin G, Marks, David I, Wilkins, Alastair, Scolding, Neil J, Rice, Claire M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029147/
https://www.ncbi.nlm.nih.gov/pubmed/28548004
http://dx.doi.org/10.1177/1352458517711276