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Left ventricular hypertrophy in experimental chronic kidney disease is associated with reduced expression of cardiac Kruppel-like factor 15

BACKGROUND: Left ventricular hypertrophy (LVH) increases the risk of death in chronic kidney disease (CKD). The transcription factor Kruppel-like factor 15 (KLF15) is expressed in the heart and regulates cardiac remodelling through inhibition of hypertrophy and fibrosis. It is unknown if KLF15 expre...

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Detalles Bibliográficos
Autores principales: Patel, Sheila K., Velkoska, Elena, Gayed, Daniel, Ramchand, Jay, Lesmana, Jessica, Burrell, Louise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029153/
https://www.ncbi.nlm.nih.gov/pubmed/29970016
http://dx.doi.org/10.1186/s12882-018-0955-9