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Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression

BACKGROUND: Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. The long non-coding RNAs (lncRNAs), emerging as key molecules in human malignancy, has become one of the hot topics in RNA biology. Abe...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zeng, Changqian, Hu, Jialei, Pan, Yue, Shan, Yujia, Liu, Bing, Jia, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029165/
https://www.ncbi.nlm.nih.gov/pubmed/29970122
http://dx.doi.org/10.1186/s13045-018-0632-2