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17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression

BACKGROUND: In non-small cell lung cancer (NSCLC), estrogen (E2) significantly promotes NSCLC cell growth via estrogen receptor beta (ERβ). Discovery and elucidation of the mechanism underlying estrogen-promoted NSCLC progression is critical for effective preventive interventions. IL6 has been demon...

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Detalles Bibliográficos
Autores principales: Huang, Quanfu, Zhang, Zheng, Liao, Yongde, Liu, Changyu, Fan, Sheng, Wei, Xiao, Ai, Bo, Xiong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029357/
https://www.ncbi.nlm.nih.gov/pubmed/29970138
http://dx.doi.org/10.1186/s13046-018-0804-5