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DNMT1 regulates expression of MHC class I in post-mitotic neurons

Major Histocompability Complex I (MHC-I) molecules present cellularly derived peptides to the adaptive immune system. Generally MHC-I is not expressed on healthy post-mitotic neurons in the central nervous system, but it is known to increase upon immune activation such as viral infections and also d...

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Detalles Bibliográficos
Autores principales: Gustafsson, Julie Ry, Katsioudi, Georgia, Degn, Matilda, Ejlerskov, Patrick, Issazadeh-Navikas, Shohreh, Kornum, Birgitte Rahbek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029374/
https://www.ncbi.nlm.nih.gov/pubmed/29970123
http://dx.doi.org/10.1186/s13041-018-0380-9