Mutant p53 gain of function induces HER2 over-expression in cancer cells

BACKGROUND: HER2 over-expression is related with a poor prognosis in patients with invasive breast cancer tumors. Clinical associations have reported that somatic mutations of p53 more frequently detected in cases of sporadic breast cancer of the HER2 subtypes, besides a high percentage of HER2-ampl...

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Detalles Bibliográficos
Autores principales: Román-Rosales, A. A., García-Villa, E., Herrera, L. A., Gariglio, P., Díaz-Chávez, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029411/
https://www.ncbi.nlm.nih.gov/pubmed/29970031
http://dx.doi.org/10.1186/s12885-018-4613-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029411/
https://www.ncbi.nlm.nih.gov/pubmed/29970031
http://dx.doi.org/10.1186/s12885-018-4613-1

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