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Overcoming Therapeutic Resistance of Triple Positive Breast Cancer with CDK4/6 Inhibition
Triple positive breast cancers overexpress both the human epidermal growth factor receptor 2 (HER2) oncogene and the hormonal receptors (HR) to estrogen and progesterone. These cancers represent a unique therapeutic challenge because of a bidirectional cross-talk between the estrogen receptor alpha...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029445/ https://www.ncbi.nlm.nih.gov/pubmed/30018827 http://dx.doi.org/10.1155/2018/7835095 |