Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation

Platelet degranulation is crucial for hemostasis and may participate in inflammation. Exocytosis in platelets is mediated by SNARE proteins and should be controlled by Munc13 proteins. We found that platelets express Munc13-2 and -4. We assessed platelet granule exocytosis in Munc13-2 and -4 global...

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Detalles Bibliográficos
Autores principales: Cardenas, Eduardo I., Breaux, Keegan, Da, Qi, Flores, Jose R., Ramos, Marco A., Tuvim, Michael J., Burns, Alan R., Rumbaut, Rolando E., Adachi, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029531/
https://www.ncbi.nlm.nih.gov/pubmed/29674495
http://dx.doi.org/10.3324/haematol.2017.185637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029531/
https://www.ncbi.nlm.nih.gov/pubmed/29674495
http://dx.doi.org/10.3324/haematol.2017.185637

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