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Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation
Platelet degranulation is crucial for hemostasis and may participate in inflammation. Exocytosis in platelets is mediated by SNARE proteins and should be controlled by Munc13 proteins. We found that platelets express Munc13-2 and -4. We assessed platelet granule exocytosis in Munc13-2 and -4 global...
Autores principales: | Cardenas, Eduardo I., Breaux, Keegan, Da, Qi, Flores, Jose R., Ramos, Marco A., Tuvim, Michael J., Burns, Alan R., Rumbaut, Rolando E., Adachi, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029531/ https://www.ncbi.nlm.nih.gov/pubmed/29674495 http://dx.doi.org/10.3324/haematol.2017.185637 |
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