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Baseline multimodal information predicts future motor impairment in premanifest Huntington's disease

In Huntington's disease (HD), accurate estimates of expected future motor impairments are key for clinical trials. Individual prognosis is only partially explained by genetics. However, studies so far have focused on predicting the time to clinical diagnosis based on fixed impairment levels, as...

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Detalles Bibliográficos
Autores principales: Castro, Eduardo, Polosecki, Pablo, Rish, Irina, Pustina, Dorian, Warner, John H., Wood, Andrew, Sampaio, Cristina, Cecchi, Guillermo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029560/
https://www.ncbi.nlm.nih.gov/pubmed/29984153
http://dx.doi.org/10.1016/j.nicl.2018.05.008