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Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma
BACKGROUND: Glutaminase (GLS), the key enzyme that catalyzes glutamine catabolism, facilitates the production of energy, building blocks, and factors resisting stresses. Two isoforms of GLS have been identified: GLS1 and GLS2. Elevated GLS1 contributes to tumorigenesis and tumor progression. This st...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029591/ https://www.ncbi.nlm.nih.gov/pubmed/29988727 http://dx.doi.org/10.2147/OTT.S167408 |