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Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma

BACKGROUND: Glutaminase (GLS), the key enzyme that catalyzes glutamine catabolism, facilitates the production of energy, building blocks, and factors resisting stresses. Two isoforms of GLS have been identified: GLS1 and GLS2. Elevated GLS1 contributes to tumorigenesis and tumor progression. This st...

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Detalles Bibliográficos
Autores principales:	Dong, Meng, Miao, Lin, Zhang, Fengmei, Li, Shengshui, Han, Jingzhi, Yu, Ruohui, Qie, Shuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029591/ https://www.ncbi.nlm.nih.gov/pubmed/29988727 http://dx.doi.org/10.2147/OTT.S167408

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