The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

OBJECTIVES: Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. This study aimed to clarify how the SLE-associated intronic STAT4 risk allele rs7574865[T] affects the function of im...

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Detalles Bibliográficos
Autores principales: Hagberg, Niklas, Joelsson, Martin, Leonard, Dag, Reid, Sarah, Eloranta, Maija-Leena, Mo, John, Nilsson, Magnus K, Syvänen, Ann-Christine, Bryceson, Yenan T, Rönnblom, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029643/
https://www.ncbi.nlm.nih.gov/pubmed/29475858
http://dx.doi.org/10.1136/annrheumdis-2017-212794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029643/
https://www.ncbi.nlm.nih.gov/pubmed/29475858
http://dx.doi.org/10.1136/annrheumdis-2017-212794

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