Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy

p-Cresol, found at high concentrations in the serum of chronic kidney failure patients, is known to cause cell senescence and other complications in different parts of the body. p-Cresol is thought to mediate cytotoxic effects through the induction of autophagy response. However, toxic effects of p-...

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Detalles Bibliográficos
Autores principales: Yun, Seung Pil, Han, Yong-Seok, Lee, Jun Hee, Kim, Sang Min, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029684/
https://www.ncbi.nlm.nih.gov/pubmed/28655071
http://dx.doi.org/10.4062/biomolther.2017.071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029684/
https://www.ncbi.nlm.nih.gov/pubmed/28655071
http://dx.doi.org/10.4062/biomolther.2017.071

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