Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials

Acanthamoeba is normally free-living, but sometimes facultative and occasionally opportunistic parasites. Current therapies are, by necessity, arduous and yet poorly effective due to their inabilities to kill cyst stages or in some cases to actually induce encystation. Acanthamoeba can therefore sur...

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Detalles Bibliográficos
Autores principales: Rice, Christopher A., Campbell, Sara J., Bisson, Claudine, Owen, Hayley J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Henriquez, Fiona L., Roberts, Craig W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029752/
https://www.ncbi.nlm.nih.gov/pubmed/29969448
http://dx.doi.org/10.1371/journal.pone.0198827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029752/
https://www.ncbi.nlm.nih.gov/pubmed/29969448
http://dx.doi.org/10.1371/journal.pone.0198827

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