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Structural and functional studies of histidine biosynthesis in Acanthamoeba spp. demonstrates a novel molecular arrangement and target for antimicrobials
Acanthamoeba is normally free-living, but sometimes facultative and occasionally opportunistic parasites. Current therapies are, by necessity, arduous and yet poorly effective due to their inabilities to kill cyst stages or in some cases to actually induce encystation. Acanthamoeba can therefore sur...
Autores principales: | Rice, Christopher A., Campbell, Sara J., Bisson, Claudine, Owen, Hayley J., Sedelnikova, Svetlana E., Baker, Patrick J., Rice, David W., Henriquez, Fiona L., Roberts, Craig W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029752/ https://www.ncbi.nlm.nih.gov/pubmed/29969448 http://dx.doi.org/10.1371/journal.pone.0198827 |
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