Utilizing host endogenous microRNAs to negatively regulate the replication of porcine reproductive and respiratory syndrome virus in MARC-145 cells

MicroRNAs (miRNAs) contribute to gene regulation at the post-transcriptional level and are capable of mRNA silencing by binding to target sites exhibiting high degrees of complementarity. Therefore, cloning host miRNA-recognition sequences into the genome of RNA viruses represents a rational strateg...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Liwei, Gao, Fei, Zheng, Hao, Jiang, Yifeng, Tong, Wu, Zhou, Yanjun, Tong, Guangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029797/
https://www.ncbi.nlm.nih.gov/pubmed/29969475
http://dx.doi.org/10.1371/journal.pone.0200029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029797/
https://www.ncbi.nlm.nih.gov/pubmed/29969475
http://dx.doi.org/10.1371/journal.pone.0200029

Ejemplares similares