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Utilizing host endogenous microRNAs to negatively regulate the replication of porcine reproductive and respiratory syndrome virus in MARC-145 cells

MicroRNAs (miRNAs) contribute to gene regulation at the post-transcriptional level and are capable of mRNA silencing by binding to target sites exhibiting high degrees of complementarity. Therefore, cloning host miRNA-recognition sequences into the genome of RNA viruses represents a rational strateg...

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Detalles Bibliográficos
Autores principales:	Li, Liwei, Gao, Fei, Zheng, Hao, Jiang, Yifeng, Tong, Wu, Zhou, Yanjun, Tong, Guangzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029797/ https://www.ncbi.nlm.nih.gov/pubmed/29969475 http://dx.doi.org/10.1371/journal.pone.0200029

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