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Vaccine immunotherapy with ARNAX induces tumor‐specific memory T cells and durable anti‐tumor immunity in mouse models

Immunological checkpoint blockade therapies benefit a limited population of cancer patients. We have previously shown that vaccine immunotherapy with Toll‐like receptor (TLR)3‐adjuvant and tumor antigen overcomes anti‐programmed death ligand‐1 (PD‐L1) resistance in mouse tumor models. In the present...

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Detalles Bibliográficos
Autores principales: Takeda, Yohei, Yoshida, Sumito, Takashima, Ken, Ishii‐Mugikura, Noriko, Shime, Hiroaki, Seya, Tsukasa, Matsumoto, Misako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029830/
https://www.ncbi.nlm.nih.gov/pubmed/29791768
http://dx.doi.org/10.1111/cas.13649