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α‐particle therapy for synovial sarcoma in the mouse using an astatine‐211‐labeled antibody against frizzled homolog 10

Synovial sarcoma (SS) is a rare yet refractory soft‐tissue sarcoma that predominantly affects young adults. We show in a mouse model that radioimmunotherapy (RIT) with an α‐particle emitting anti‐Frizzled homolog 10 (FZD10) antibody, synthesized using the α‐emitter radionuclide astatine‐211 ((211)At...

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Detalles Bibliográficos
Autores principales: Li, Huizi Keiko, Sugyo, Aya, Tsuji, Atsushi B., Morokoshi, Yukie, Minegishi, Katsuyuki, Nagatsu, Kotaro, Kanda, Hiroaki, Harada, Yosuke, Nagayama, Satoshi, Katagiri, Toyomasa, Nakamura, Yusuke, Higashi, Tatsuya, Hasegawa, Sumitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029834/
https://www.ncbi.nlm.nih.gov/pubmed/29952132
http://dx.doi.org/10.1111/cas.13636