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Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages

Ninety percent of hepatocarcinoma (HCC) develops in a chronically damaged liver. Interactions between non‐tumor stromal components, especially macrophages, and cancer cells are still incompletely understood. Our aim was to determine whether a chronically injured liver represents a favorable environm...

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Detalles Bibliográficos
Autores principales: Delire, Bénédicte, Henriet, Patrick, Lemoine, Pascale, Leclercq, Isabelle A., Stärkel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029836/
https://www.ncbi.nlm.nih.gov/pubmed/29727510
http://dx.doi.org/10.1111/cas.13628