Cargando…
Chronic liver injury promotes hepatocarcinoma cell seeding and growth, associated with infiltration by macrophages
Ninety percent of hepatocarcinoma (HCC) develops in a chronically damaged liver. Interactions between non‐tumor stromal components, especially macrophages, and cancer cells are still incompletely understood. Our aim was to determine whether a chronically injured liver represents a favorable environm...
Autores principales: | Delire, Bénédicte, Henriet, Patrick, Lemoine, Pascale, Leclercq, Isabelle A., Stärkel, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029836/ https://www.ncbi.nlm.nih.gov/pubmed/29727510 http://dx.doi.org/10.1111/cas.13628 |
Ejemplares similares
-
Animal Models for Fibrotic Liver Diseases: What We Have, What We Need, and What Is under Development
por: Delire, Bénédicte, et al.
Publicado: (2015) -
Aging enhances liver fibrotic response in mice through hampering extracellular matrix remodeling
por: Delire, Bénédicte, et al.
Publicado: (2016) -
Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition
por: Charette, Nicolas, et al.
Publicado: (2010) -
Salirasib sensitizes hepatocarcinoma cells to TRAIL-induced apoptosis through DR5 and survivin-dependent mechanisms
por: Charette, N, et al.
Publicado: (2013) -
Immunotherapy and Gene Therapy: New Challenges in the Diagnosis and Management of Drug-Induced Liver Injury
por: Delire, Bénédicte, et al.
Publicado: (2022)