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Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury

Neuropathic pain resulting from nerve injury can become persistent and difficult to treat but the molecular signaling responsible for its development remains poorly described. Here, we identify the neuronal stress sensor dual leucine zipper kinase (DLK; Map3k12) as a key molecule controlling the mal...

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Detalles Bibliográficos
Autores principales: Wlaschin, Josette J, Gluski, Jacob M, Nguyen, Eileen, Silberberg, Hanna, Thompson, James H, Chesler, Alexander T, Le Pichon, Claire E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029846/
https://www.ncbi.nlm.nih.gov/pubmed/29968565
http://dx.doi.org/10.7554/eLife.33910