Suppression of STING Signaling through Epigenetic Silencing and Missense Mutation Impedes DNA-Damage Mediated Cytokine Production

The production of cytokines in response to DNA damage events may be an important host defense response to help prevent the escape of pre-cancerous cells. The innate immune pathways involved in these events are known to be regulated by cellular molecules such as STING (stimulator of interferon genes)...

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Detalles Bibliográficos
Autores principales: Konno, Hiroyasu, Yamauchi, Shota, Berglund, Anders, Putney, Ryan M., Mulé, James J., Barber, Glen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029885/
https://www.ncbi.nlm.nih.gov/pubmed/29367762
http://dx.doi.org/10.1038/s41388-017-0120-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029885/
https://www.ncbi.nlm.nih.gov/pubmed/29367762
http://dx.doi.org/10.1038/s41388-017-0120-0

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