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Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation

Activation of the T cell receptor (TCR) leads to the generation of a network of signaling events critical to the developmental decision making and activation of T cells. Various experimental approaches continue to identify new signaling molecules, adaptor proteins, and other regulators of TCR signal...

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Detalles Bibliográficos
Autores principales: Chen, Elijah W., Brzostek, Joanna, Gascoigne, Nicholas R. J., Rybakin, Vasily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030045/
https://www.ncbi.nlm.nih.gov/pubmed/29968737
http://dx.doi.org/10.1038/s41598-018-28106-5