Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration

The tumor form of pyruvate kinase M2 has been suggested to promote cellular anabolism by redirecting the metabolism to cause accumulation of glycolytic intermediates and increasing flux through the pentose phosphate pathway, which is a metabolic pathway parallel to glycolysis. Both rod and cone phot...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajala, Ammaji, Wang, Yuhong, Soni, Krutik, Rajala, Raju V. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030055/
https://www.ncbi.nlm.nih.gov/pubmed/29970877
http://dx.doi.org/10.1038/s41419-018-0712-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030055/
https://www.ncbi.nlm.nih.gov/pubmed/29970877
http://dx.doi.org/10.1038/s41419-018-0712-9

Ejemplares similares