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Pyruvate kinase M2 isoform deletion in cone photoreceptors results in age-related cone degeneration
The tumor form of pyruvate kinase M2 has been suggested to promote cellular anabolism by redirecting the metabolism to cause accumulation of glycolytic intermediates and increasing flux through the pentose phosphate pathway, which is a metabolic pathway parallel to glycolysis. Both rod and cone phot...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030055/ https://www.ncbi.nlm.nih.gov/pubmed/29970877 http://dx.doi.org/10.1038/s41419-018-0712-9 |