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Uhrf1 regulates active transcriptional marks at bivalent domains in pluripotent stem cells through Setd1a
Embryonic stem cells (ESCs) maintain pluripotency through unique epigenetic states. When ESCs commit to a specific lineage, epigenetic changes in histones and DNA accompany the transition to specialized cell types. Investigating how epigenetic regulation controls lineage specification is critical in...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030064/ https://www.ncbi.nlm.nih.gov/pubmed/29968706 http://dx.doi.org/10.1038/s41467-018-04818-0 |